Copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazole based ligands and their catalytic activity in azide-alkyne cycloaddition.

نویسندگان

  • Daniel Mendoza-Espinosa
  • Guillermo Enrique Negrón-Silva
  • Deyanira Ángeles-Beltrán
  • Alejandro Álvarez-Hernández
  • Oscar R Suárez-Castillo
  • Rosa Santillán
چکیده

The preparation and characterization of four new copper(ii) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazoles are reported. The four complexes display a 1 : 2 copper/ligand ratio and give monomeric units in the solid state. Crystal structures demonstrate that depending on the flexibility of the ligand NX (X = O, N, S) pendant arm, the coordination environment around the metal center can feature square planar or octahedral geometries. All four complexes are catalytically active at room temperature in a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction using sodium ascorbate as a reducing agent and water-ethanol as a solvent mixture. Complex 8 supported by the NS ligand displayed the best catalytic performance of the series allowing for the easy and high yielding preparation of a variety of mono-, bis- and tris-1,2,3-triazoles under low catalyst loadings.

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عنوان ژورنال:
  • Dalton transactions

دوره 43 19  شماره 

صفحات  -

تاریخ انتشار 2014